REVIEW ARTICLE


Research Trends in Plant-Derived Oligomers for Health Applications



Merve Deniz Kose1, John G. Hardy2, 3, Emer Sheridan4, Feyruz Bozoğlan5, Oguz Bayraktar6, *
1 Department of Chemical Engineering, Faculty of Engineering, Ege University, İzmir, Turkey;
2 Department of Chemistry, Lancaster University, Lancaster, UK,
3 Materials Science Institute, Lancaster University, Lancaster, UK,
4 Department of Pharmacy, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK;
5 NPRO Ltd Co., İzmir, Turkey;
6 Department of Bioengineering, Faculty of Engineering, Ege University, İzmir, Turkey


Copyright: 2021 Bentham Science Publishers

* Address correspondence to this author at the Department of Bioengineering, Faculty of Engineering, Ege University, P.O. Box: 35100, İzmir, Turkey; Tel/Fax: +90-232-311-2105, +90-232-388-7776; E-mail: oguz.bayraktar@ege.edu.tr


Abstract

Objective: Epidemiological data illustrates that there is a strong relationship between dietary intake of natural bioactive compounds and their beneficial properties against various diseases, and this stimulates academic and industrial interest in using plant-derived compounds for health and making medicines. For this reason, recent health related studies in the literature have focused on a variety of many plant-derived bioactive compounds. Even though the bioactivities of such compounds have widely been investigated, there are few studies about oligomeric species and their activities.

Methods: In this review, extraction and isolation methods of the plant-derived oligomers and the use of such oligomers in health applications are summarised.

Results: In the literature, many studies state that oligomeric compounds have benefits to human health. To maximize these beneficial properties, various ways to use oligomeric compounds have been examined and summarised.

Conclusion: A better understanding of the specific activities of distinct components of plant-derived oligomers is expected to open new avenues for drug discovery. This review gives an overview of oligomers with health beneficial properties and their possible applications in healthcare.

Keywords: Plant-derived oligomers, oligopeptides, oligosaccharides, probiotics, prebiotics, drugs delivery systems, health applications, functional foods.




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